Warfarin is a coumarin oral anticoagulant widely used in clinical practice. It has been used in the anticoagulant treatment of various diseases. The initial use of warfarin anticoagulant therapy can easily lead to serious bleeding complications. It is estimated that 15.2% of patients taking warfarin have bleeding side effects each year, of which fatal bleeding accounts for 3.5%, and the difference between different individuals in stable warfarin doses can be more than 20 times.

　　本试剂盒检测CYP2C9(430C>T、1075A>C)和VKORC1(-1639G>A)基因的多态性，确定患者的华法林代谢速率类型，正确选择药物并合理调整用药剂量，保证药物疗效并减少出血风险。

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