MTHFR C677T gene polymorphism detection kit (fluorescence PCR method)

Folic acid is a compound composed of pteridine, p-aminobenzoic acid and glutamic acid, and is a water-soluble B vitamin. Studies have found that folic acid is especially important for pregnant women, such as lack of folic acid within the first 3 months of pregnancy, can lead to fetal neural tube development defects, thereby increasing the incidence of split-brain and anencephaly. Excessive folic acid supplementation can increase the risk of colorectal cancer and breast cancer in pregnant women, develop allergic symptoms, affect the absorption of zinc, and lead to abnormal fetal development. Scientific research has confirmed that the MTHFR gene is closely related to folic acid metabolism, and the corresponding decrease in enzyme activity caused by these gene variants can inhibit the conversion of homocysteine ​​to methionine, resulting in hypofolate and hyperhomocysteinemia. disease, thereby increasing the risk of neonatal birth defects or spontaneous miscarriage.

By detecting the polymorphism of the MTHFR C677T gene, this kit determines the folic acid metabolism ability of the tested population, assists doctors in evaluating the risk of neonatal neural tube defects, gestational hypertension and other diseases during the perinatal period, and determines the individual of folic acid. Supplementary program.